Antimalarial drug effective alternative to canagliflozin in type 2 diabetes
Adults with type 2 diabetes inadequately controlled with a DPP-IV inhibitor plus metformin therapy experienced an improvement in glycemic control with the antimalarial drug hydroxychloroquine that was similar to the SGLT2 inhibitor canagliflozin, according to study data presented here. Source: Antimalarial drug effective alternative to canagliflozin in type 2 Read more
Malnourished HF Patients Face Significant Mortality Risk
It may be important to consider the potential prognostic value of malnutrition in heart failure, researchers suggested. Source: Malnourished HF Patients Face Significant Mortality Read more
A Patient’s Journey: Taming the Glucose Monster
In a matter of six months, a man went from diabetic levels of A1c to normal levels. Source: A Patient’s Journey: Taming the Glucose Read more
Experimental Drug Switches Off Hunger in Patients with Genetic Obesity
Investigator-initiated Phase II study finds setmelanotide therapy in patients with leptin receptor gene mutations leads to dramatic reductions in appetite and body weight. Source: Read more
Yogurt reduces inflammation, cardiometabolic risk
Eating yogurt reduced biomarkers tied to chronic inflammation and the risk for cardiometabolic disease in healthy women who had not reached menopause, according to two recently published Read more
Gut microbiome linked to artery health
Women with lower diversity of “healthy” gut bacteria showed greater arterial stiffness, suggesting that altering the gut microbiome with diet, medication or probiotics could play a role in preventing cardiovascular disease, according to new research published in the European Heart Journal. Source: Gut microbiome linked to artery Read more
After bariatric surgery, first-year weight loss may be key to improved, long-term glycemic control
In adults with obesity and type 2 diabetes who underwent bariatric surgery, acute, first-year weight loss was associated with improved HbA1c at 5 years even if the patient experienced weight regain during follow-up, according to a post hoc analysis of the STAMPEDE trial presented at the American Association of Clinical Endocrinologists annual meeting. Source: After... Read more Read more
Celiac Testing Paradigm Underdetects Disease
Currently accepted indications for celiac disease testing are ineffective and fail to discriminate between patients with and without undiagnosed celiac disease, according to a case-control Read more
Diabetes education program ‘nudges’ patients toward better health
A digital health coaching program employing weekly telephone, text messaging and email contacts helped adults with type 2 diabetes lose weight, reduce HbA1c and maintain those benefits for a year, according to study results presented here. Source: Diabetes education program ‘nudges’ patients toward better Read more
Valeritas touts new data for insulin delivery device
Valeritas (NSDQ:VLRX) touted data today from two new studies of its V-Go wearable insulin delivery device in patients with Type II diabetes. In one three-month evaluation of 60 people with Read more