
A Potential New Oral Med for Type 1 Diabetes: Insulin & Exercise Effects

For most children and adults with type 1 diabetes, day-to-day disease management remains difficult despite improvements in insulin formulations and delivery and advancements in diabetes technologies during the past decade.Only 17% of children and 21% of adults with type 1 diabetes meet HbA1c targets outlined in American Diabetes Association guidelines.
Source: Providers, regulators explore type 2 therapies for type 1 diabetes
Endocrine Today | PoinTAll pumps on the market offer several useful features for people with type 1 diabetes. These include multiple basal rate options, square- and dual-wave bolus features, the ability to calculate a suggested bolus dose based on insulin to carb ratio, insulin-on-board features to avoid insulin “stacking,” occlusion and reservoir alarms, and data downloading capabilities.
Source: Is insulin pump therapy superior to multiple daily injections in type 1 diabetes?
For children with type 1 diabetes(T1D), adverse effects on bone mineral density (BMD) begin early in the course of disease, according to study results published in The Journal of Clinical Endocrinology & Metabolism.
Source: Type 1 Diabetes Has Early Adverse Effects on Bone Mineral Density – Endocrinology Advisor
Long disease duration and an HbA1c of at least 7.9% are independent risk factors for sustaining multiple fractures among adults with type 1 diabetes, according to findings from a cross-sectional analysis published in Bone.
Source: Glycemic control, disease duration predict fracture risk in type 1 diabetes
Researchers have identified three distinct patterns of dysglycemia in adolescents with type 1 diabetes using a combination of blinded continuous glucose monitoring data and machine-learning techniques, offering clinicians an opportunity to better tailor therapy, according to findings published in Pediatric Diabetes. “The study demonstrates that among adolescents with type 1 diabetes and
Source: CGM, machine learning reveal dysglycemia phenotypes in type 1 diabetes
Adults with long-standing type 1 diabetes and hypoglycemia unawareness using an insulin pump therapy system with an algorithm-driven, insulin-suspension feature experienced fewer hypoglycemic events than those using sensor-augmented pump therapy, according to findings published in The Lancet Diabetes & Endocrinology.
Source: ‘Suspend-before-low’ feature reduces hypoglycemia with pump therapy in type 1 diabetes
Structured support for patients transitioning from pediatric to adult care for type 1 diabetes may improve outcomes, but those benefits are not sustained after completion of the intervention, according to a study published online April 22 in Diabetes Care.
Source: Transition Support Program May Aid Young Adults With Type 1 Diabetes