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Insulin preparation | Onset of action | Peak | Duration of action |
Glusaline (Apidra) | 10-30 minutes | 1/2- 2 hours | 3-5 hours |
Lispro (Humalog) | <15 minutes | 1-2 hours | 3-6 hours |
Aspart (Novolog) | <15 minutes | 1-2 hours | 3-6 hours |
Glulisine (Apidra) | <15 minutes | 1-2 hours | 3-6 hours |
Regular (Novolin R, Humulin R) | 30-60 minutes | 2-4 hours | 6-10 hours |
Humulin R Regular U-500 (500 units/ml) | 30-60 minutes | 2-4 hours | Up to 24 hours |
NPH (Novolin N, Humulin N, ReliOn) | 2-4 hours | 4-8 hours | 10-18 hours |
Glargine (Lantus) | 1-2 hours | Usually no peak | Up to 24 hours |
Detemir (Levemir) | 1-2 hours | Usually no peak ** | Up to 24 hours** |
Glargine Injection (300units/ml Toujeo) | 6 hours | No true peak | 24-36 hours |
Degludec (Tresibia 200units/ml) | 6 hours | No peak | Up to 42 hours |
Premixed Insulins | Onset of action | Peak | Duration of action |
Novolin 70/30, Humulin 70/30 |
30-60 minutes | 2-10 hours | 10-18 hours |
Humalog 75/25, Novolog 70/30, Humalog 50/50 |
10-30 minutes | 1-6 hours | 10-14 hours |